Pro-subtilis: Questions & Answers [FAQ]
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Pro-subtilis

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Frequently asked questions (FAQ)

How to use

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How long it will take for Pro-subtilis to have effect?

You may start noticing the beneficial effects of Pro-subtilis within 24-48 hours, such as reduced bloating, diarrhea, or constipation. 

Other benefits related to the production of short-chain fatty acids (SCFAs), which support overall gut health, may take a week or two to become apparent.

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How long should I take Pro-subtilis?

Bacillus subtilis DE111® germinates in the intestines, however it does not persist there for long there and making it safe for regular use. 

To experience its benefits, it's recommended to take 1 capsule of Pro-subtilis consistently daily or at least every other day.

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How shall I take Pro-subtilis?

In order to observe positive effects, it's best to take Pro-subtilis with food. Bacillus subtilis DE111® as many other probiotic strains need substrate from food, such as carbohydrates and fibre, to germinate and multiply and produce the very helpful for the intestines SCFA(short chain fatty acids).

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Can I open the capsules and dissolve the contents in water?

Yes, you can. Bacillus subtilis DE111® is one of the few probiotic strains that can survive stomach acid without protection due to its ability to form spores. While Pro-subtilis capsules are acid-resistant, opening the capsules and dissolving the contents will not negatively affect the germination of Bacillus subtilis DE111® in the small intestines.

Composition

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Does Pro-subtilis capsules contain palm oil?

All hard capsule and tablet products require small amounts of additives known as lubricants, which reduce friction during the manufacturing process.

These lubricants typically include triglycerides derived from palm or coconut oil, and sometimes magnesium stearate, which is only permitted in pharmaceutical products. In food supplements in the form of hard capsules and tablets palm or coconut oil-based triglycerides are used as lubricants. 

However, since these additives are used in quantities of less than 1%, they have no significant physiological effect.

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Does Pro-subtilis contain gluten?

Pro-subtilis capsules  are vegan and gluten free.

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Is Bacillus subtilis DE111® strain safe?

Yes, Bacillus subtilis DE111® is considered one of the safest probiotic strains available. The manufacturer, Deerland, has conducted full genome sequencing and holds the following certifications:

  • FDA-Notified GRAS (Generally Recognized as Safe)
  • Organic compliant
  • Star-K Kosher certified
  • Non-GMO Project Verified
  • Approved by Health Canada as a natural product
  • Recognized as non-novel food in Canada, Australia, and New Zealand
  • NASC preferred supplier.


In fact, there are more than 30 studies to confirm the safety and efficacy of Bacillus subtilis DE111®.

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What is the size of Pro-subtilis capsules?

The size of Pro-subtilis capsules is size “1” vegetable capsule.
Size “1” capsules are a bit smaller than the most common size “0”.

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What material Pro-subtilis packaging made of?

The packaging is produced by Nolato Cerbo (Sweden) and is made of PE-HD(polyethylene high density) and PE-LD 
The bottle and the cap are tested and certified to be BPA free.

Storage

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How Pro-subtilis should be stored?

Pro-subtilis can be stored at room temperature or in the refrigerator, though the latter is not necessary. 

Storage at room temperature guarantees a minimum of 5 billion CFU of Bacillus subtilis per capsule by the end of its expiration date.

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Should I close the bottle immediately after use?

Yes, it is essential to close the cap containing the desiccant after use. Like most probiotic strains, moisture can deteriorate Bacillus subtilis DE111® 

Label

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What are the nutritional claims of Pro-subtilis?

 Bacillus subtilis DE111® has a balancing role on the intestinal flora and supports the normal functioning of the intestines - digestion, proper peristalsis, immune role, athletic strength and recovery.  Bacillus subtilis DE111® helps maintain a healthy balance in the gut microbiome and promotes optimal digestive function, regular peristalsis, immune system support, as well as aiding in athletic performance and recovery.

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What are the contents of Pro-subtilis capsules?

Bulking agents: rice maltodextrin, Bacillus subtilis DE111® - 20.8mg, anti-caking agents: Triglycerides (medium chain) from coconut/palm oil, capsule (vegetable) - hydroxymethyl propyl cellulose.

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Where Pro-subtilis is produced?

Bacillus subtilis DE111® and the capsules are produced in bulk by Deerland Probiotics & Enzymes Inc. in the USA. The finished capsules are then bottled at a HACCP-certified food supplement facility in the EU.


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